Abstract

GRANADILLO, G; CLAUDIO, E; GUERRA, M  and  ZUNIGA, M. Premedicación con Ketorolac para Analgesia Postoperatoria en Cirugía Ginecológica. AVFT [online]. 2001, vol.20, n.1, pp.69-79. ISSN 0798-0264.

The objetive of the investigation was to verify the effectiveness of the use of the Ketorolac in the premedication for post-operative analgesia in Gynecological Surgery. 50 patients were studied programmed for Abdominal Hysterectomy, divided in two groups in aleatory form:Group A or Control (n=25) and group B or Experimental (n=25) that Ketorolac 30 mg received EV 20 minutes before the induction of the anesthesia, both groups were similar regarding the age, A.S.A and time of Surgery, in the two groups parameters hamodynamic pre were measured, trans and postoperative, duration of the analgesia and incidence of adverse effects. The numeric variables will be analyzed with the test of standard desviation and student T. They are obtain as results of parameters hemodynamic transoperatives: Group A TAS (114,6 +/- 11.98), TAD (72.4+/-7.03) and FC (86.0 +/-7.41) and Group B TAS (100.3 +/- 5.10), TAD (61.6 +/- 6.26) and FC (72.4 +/- 7.03) (P<0.0001) that indicated a very significant difference, in a same way the postoperative hemodynamic parameter showed that extremely significant differences exited for the Group A:TAS (127.9 +/- 14.3), TAD (84.2 +/- 7.01) and FC (93.5 +/-9.3) in connection with the Group B:TAS (111.4 +/- 10.5), TAD (73.4 +/- 6.9) and FC (73.4 +/- 6.95). The variable postoperative analgesia was of 0.25 +/- 0.20 in the Group A and of 4.8 +/- 0.76 for the B, it indicated a very significant difference (P<0.0001). Important adverse effects are not observed.You concludes that Ketorolac EV´S administration in the premedication represente an effective alternative to reduce the pain in the postoperative one immediate in Gynecological Surgery with a low incidence of adverse effects.

Keywords : ketorolac preoperatory; Postoperative analgesia.