Abstract

DEL NOGAL, B et al. Fluconazol versus Nistatina en niños con Candidiasis Orofaríngea. AVFT [online]. 2001, vol.20, n.1, pp.92-98. ISSN 0798-0264.

The Oropharyngeal Candidiasis constitute a frecuent pathology in the pediatric population. In order to offer a safe and efficient therapeutic alternative, an multicentric, prospective, single blind and randomized study was performed 181 patients which included clinic and micologic diagnostic of Orofaringeal Candidiasis; they were asigned in a randomized way to received fluconazole suspensión containing 5 mgrs/Kg once daily or Nystatin suspensión 50.000 units/Kg every six hours. Satisfactory clinic response was obtained at the end of the treatment with a very significant statistic difference (p<0.001) in the fluconazole group compared to the nystatin group. A month later the clinical response was very significant (p< 0.01). The mycological erradication reported a very high significant response p<0.0002 in the fluconazole group. The use of fluconazole oral suspensión is presented as an efficient therapeutic, well tolerated and with posologic confort in the pediatric age. The Candida albicans was isolated in 92% of the cases.

Keywords : Oropharingeal candidiasis; Fluconazole.