Resumo

A PEREZ, Puigbó; E CAPRILES, Behrens  e  L GIANNONI, Delgado. Nebulized Saline Solution of Dry Powder Formoterol is Useful for Acute Bronchospasm. AVFT [online]. 2001, vol.20, n.2, pp.128-130. ISSN 0798-0264.

Salmeterol and Formoterol, two new long acting Beta agonists, are being clinically employed. Salmeterol lacks efficacy in acute asthma while Formoterol, with a latency period similar to albuterol, has never been used in the acute bronchospastic situation. We measured peak expiratory flows in 30 acute asthma patients with variable degrees of airway obstruction before and after administation of 12 micrograms of Formoterol Fumarate (Foradil®) dry powder, nebulized inmediatly after preparation in sterile saline solution. We found significant improvements at 5 and 30 minutes after administration suggesting stability of this product and a possible new cost effective approach with a need for less dosing and perhaps an impact on the rate of asthma readmisions due to the prolonged bronchodilatador effect.

Palavras-chave : Formoterol; Nebulized solution; Asthma acute management; Long acting Beta 2 agonist.