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Archivos Venezolanos de Farmacología y Terapéutica

versión impresa ISSN 0798-0264

Resumen

SOUKI, A et al. Comportamiento del perfil lipídico en una muestra de población adulta de la ciudad de Maracaibo. AVFT [online]. 2003, vol.22, n.1, pp.35-39. ISSN 0798-0264.

ABSTRACT     Diverse investigations have established a relationship between an altered lipid profile and higher risk of cardiovascular diseases, which have their highest incidence in adult people. For this reason it was considered necessary to know the lipid profile behavior in a sample of this population. 186 individuals over 40 years of age and from Maracaibo, were chosen at random order. They were divided by age groups (40-49y, 50-59y, 60y and over) and by gender (94 men, M, 92 women, W). Serum concentrations of total cholesterol (TC), Triacilglycerides (TAG) and HDL-col were determined; the Friedwald formulas were used for the remaining fractions. TC (mg/dl) showed a significant statistical difference in relation with gender in the age group 60y and over (176,9±4,7-M Vs 200,1±4,9-W), and also between men of each age group (193,5±9,0 Vs 192,2 ±11,2 Vs 176,9±4,7). Tryacilglicerides (mg/dl) showed a significant statistical difference between men age groups (221,15±21.84 Vs 170,96±17,94 ± Vs 131,45±6,871) and according to sex in the age group 40-49y (221,1±21,8- M Vs 149,8±9,7-W) and 60y and over 131,4±6,8-M Vs 157,7±9,8-W). HDL-col (mg/dl) levels showed differences according to sex in all age groups, 40-49y (39,3±1,5-M Vs 48,3±1,7-W), 50-59y (37,3±1,21-M Vs 45,2±1,7-W), 60y and over (41,4±1,4-M Vs 45,8±1,21-W). VLDL-col (mg/dl) concentrations showed difference in each of the men’s age groups (44,2±4,3 Vs34,1±3,5 Vs 26,3±1,3), also between sex for the age groups 40-49y (44,2±4,3-M Vs 29,9±1,9-W) and 60y and over (26,2±1,3-M Vs 31,5±1,91-W). The sutdy showed a decrease in the TC and TAG levels in the age groups of 60y and over, likewise there were significant differences in the HDL-col levels between sex for all age groups studied. These differences were probably due to genetic and environmental factors.

Palabras clave : Adult population; Lipid profile; Risk for ischemic diseases.

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