Resumo

SUTIL DE NARANJO, R et al. Niveles de Vitaminas Antioxidantes y Lípidos en escolares con historia familiar de enfermedad arterial coronaria. AVFT [online]. 2003, vol.22, n.2, pp.172-180. ISSN 0798-0264.

ABSTRACT An evaluation was carried-out on the antioxidant vitamins A, E, C and lipids profile in 50 school children whose parents had suffered coronary artery disease (CAD) before reaching the age of 55 years (study group) in comparison with a control group of 46 school children with healthy parents. Serum Vitamin A (Retinol) and E (Tocopherol) were determined by HPLC and Vitamin C (Ascorbic acid) and lipids were assayed by colorimetric methods. These results showed no significant differences between groups for absolute values of vitamin E, A and C. However, when Vitamin E was standardized for lipids, Total Cholesterol (TC) or TC + Triglycerides (TG), Vitamin E values were lower (p£0.05) in the study group than in the control group (Vitamin E/TC 3.48±1.52 mM/mM and Vitamin E/TC+TG 2.82±1.24 mM/mM) versus (Vitamin E/TC 4.60±2.10 mM/mM and Vitamin E/TC+TG 3.83±1.67 mM/mM). Additionally, risk indexes were significantly higher (p£0.05) in the study group. These results indicate that school children with history family of early CAD shown deficiencies antioxidant Vitamin E and lipids profile alteration.

Palavras-chave : School children; Antioxidant vitamins; Lipids; Family history Coronary Artery Disease.