Resumen

MAGALDI, L; ALVIS, J  y  CORREA, D. Farmacovigilancia de los Agonistas Adrenérgicos en pacientes de la unidad de cuidados intensivos del hospital "Dr. Miguel Pérez Carreño". AVFT [online]. 2004, vol.23, n.1, pp.50-53. ISSN 0798-0264.

A descriptive study was made in 84 patients to determined adverse drugs reactions (DAR) during the IV treatment with some of the following adrenergic agonists: norepinephrine (0,5m/kg/min), epinephrine (0.1m/kg/min), dopamine (3m/kg/min.) and dobutamine (5m/kg/min). The Yellow Card of CEVIFARE was used as the instrument for registry of the DAR. DAR were analyzed by its type, severity and causality. 83.33% of the patients had DAR, being most frequent: tachycardia (47,61%), pallor (23,80%), hypertension (11,90%) and arrhythmias (7,14%). All the DAR were type A, mild 50%, moderate 40% and serious 10%. 100% of DAR analyzed were proved. Although the adrenergic agonists turned out to be safe, the epinephrine has the risk of producing distal necrosis, thus the Nursing role in practicing pharmacovigilance is to prevent or to diminish the possibility of appearance of DAR in the patients under her care.

Palabras clave : Pharmacovigilance; DAR; Adrenergic agonists; Nursing role.