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Archivos Venezolanos de Farmacología y Terapéutica
versión impresa ISSN 0798-0264
Resumen
TOMASZ ROS, LESZEK. A correlation between demographic factors and therapeutic effects of Paroxetina in the endogeneous depression syndrome. AVFT [online]. 2007, vol.26, n.1, pp.70-75. ISSN 0798-0264.
Objectives. The analysis of correlation of therapeutic efficiency of Paroxetina with demographic factors (sex, age, financial conditions, education, number of diseases, intensity of depression, actual emotional state, religious outlook on life and professional status). Methods. The total number of 99 patients were chosen for the study. Patients were treated with Paroxetina due to a "major depression" syndrome. Data for the study were taken from the diseases history of the persons. Patients were observed for six weeks. Each patient was individually examined by the psychiatrist and was diagnosed according to 24 points Hamilton Depression Evaluation Scale, Beck Depression Self-Assessment Inventory, Montgomery-Asberg Scale and CGI Scale, which allowed for the evaluation of the effects of the treatment. Results. Significantly good effects of the treatment of "major depression" were obtained for men with high education in whom light depression syndrome occurred not much more than three times in life. Very good results were observed in about 27% of active believer patients. Whereas such demographic factors like age of the patients, financial conditions, actual emotional state and professional status had only little impact on therapeutic effects of the depression. Conclusions. It has turned out that only some demographic factors clearly correlate with the therapeutic effects of the depression. Best effects of the treatment with Paroxetina were obtained for men with high education in whom not many light depression syndrome occurred in life. Some other demographic factors clearly correlate with the effect of treatment of the depression with Sulpiride.
Palabras clave : major depression; demographic factors; therapeutic effects.