Resumo

ALMARZA, J et al. Ácidos grasos trans y riesgos cardiovascular. AVFT [online]. 2007, vol.26, n.2, pp.87-91. ISSN 0798-0264.

Trans Fatty acids and cardiovascular risk Trans fatty acids are an isomeric variant produced during hydrogenation and heating of non saturated fats industrial processes. It has been established an epidemiological relationship between Trans fatty acids and the development of isquemic cardiac atack, but the underlying mechanisms have not been clarified completely. The atherogenic effects of trans fatty acids are related to a lipid profile expressed by high levels of Low Density Lipoproteins (LDL), low levels of High Density Lipoproteins (HDL) and hyperlipoproteinemia (a), increasing the risk for the development of atherogenic processes and miocardial infarction. They also interfere in metabolism of eicosanoids contributing to a prothrombotic state. This review pretends to illustrate molecular mechanisms related to the paper of trans fatty acids on elevation of cardiovascular diseases risk.

Palavras-chave : Lipoproteins; Trans fatty acids; atheroesclerosis.

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