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Archivos Venezolanos de Farmacología y Terapéutica

versão impressa ISSN 0798-0264

Resumo

SCORZA, Tosca I; ORTIZ, Holger Neptalí; RODRIGUEZ S, Oscar  e  ALFONSO-PEREZ, Candelaria. Efecto del consumo de aceite crudo de palma o maíz sobre la oxidación in vitro de la HDL plasmática de conejos: Oxidación in vitro de HDL de conejos. AVFT [online]. 2007, vol.26, n.2, pp.115-119. ISSN 0798-0264.

We investigated the in vitro susceptibility to copper-induced oxidation of the rabbits HDLs fed during 3 months with 10 % supplementary diet of crude palm oil or corn oil. The isolated HDLs by ultracentrifugation were dializated  and oxidated following the addition of 10 µM Cu2+, the conjugated dienes were analysed by spectroscopic monitoring at 234 nm. The kinetics change of lag-phase of the group feed with crude palm oil was longer (145 min) with respect to the group feed with corn oil (94 min) (p<0,05). We concluded that the consumed of the crude palm oil, rich in carotenes and tocotrienols, increase the protection in vitro of HDLs unsatured fatty acids oxidation.

Palavras-chave : HDL oxidation; palm oil; rabbit.

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