Resumen

SOUKI-RINCON, A et al. Variaciones por Edad y Sexo en el HOMAIR, en los niveles de Insulina y Glucosa séricas en niños y adolescentes de Maracaibo-Estado Zulia. AVFT [online]. 2007, vol.26, n.2, pp.135-1341. ISSN 0798-0264.

Objective: Variations of insulin resistance index and the serum concentrations of glucose and insulin among children and adolescents are poorly investigated in Venezuelan pediatric population. The aim of this study was to describe the variations of fasting plasma insulin, glucose and HOMAIR in sample of children and adolescents from Maracaibo-Zulia-Venezuela. Methods: A sample of 256 children and adolescents (120 girls and 136 boys) between 2 and 18 years old were studied. A medical and nutritional history was made which included body mass index (BMI), waist circumference (WC), subcutaneous skinfolds and blood pressure (BP) measurements. Fasting seric insulin and glucose were determined and the homeostatic model assessment (HOMA) index was calculated as an indicator of insulin resistance. Results: In all age and gender groups, no significant differences were found in glucose levels. However insulin concentration and HOMAIR index were significantly higher in the 14-18 years old female group (p < 0.001) when they were compared with males. The mean HOMAIR value and insulin level were higher in 10-13 years old girls and boys groups (p < 0.05). Conclusions: The glucose concentrations exhibited tight distributions in all age and sex groups. The mean concentrations of glucose were lower in our population than in other pediatric population. The increases in insulin concentrations and in HOMAIR index were observed in the 10-13 years old group from both genders.

Palabras clave : Children; adolescents; Insulin; Insulin resistance; HOMAIR index.

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