Resumo

Effectiveness of the standardized extract of leaves of Petasites Hybridus (Tesalin^®) in the treatment of allergic rhinitis. AVFT [online]. 2012, vol.31, n.1, pp.11-16. ISSN 0798-0264.

Background: Allergic rhinitis is a common condition, high social impact, and impaired quality of life, which leads to frequent change of medication, and the use of more than one drug, without adequate control of symptoms. Methods: We evaluated the evolution of clinical symptoms in 927 patients with a history of seasonal allergic rhinitis and symptomatic, with no indication of antibiotic therapy in the two weeks before, that receiving standarized extract of leaves of Petasites Hybridus Ze339 (Tesalin^®). The symptoms of allergic rhinitis were recorded in the visits to their doctors on days 0, 7, 14 and 28 after starting treatment. Patients were treated with standarized extract of leaves of Petasites Hybridus Ze339 (Tesalin^®) one tablet two or three times a day for 28 days, allowed any concomitant medication except antibiotics. The effectiveness and tolerance analysis was performed by both the physician and patient. Results: For physicians, the percentage of patients who were completely free of symptoms it was very mild, was of 94.71%, while for the patients was 95.90%, with an excellent correlation between both. Tolerance was good for the doctor (90.70%) and patients (94.47%) (P 0.95). Conclusions: The standarized extract of leaves of Petasites Hybridus Ze339 (Tesalin^®) is effective and safe in treating the symptoms of allergic rhinitis is not complicated.

Palavras-chave : Petasites hybridus; rhinitis.