Resumo

GARCIA ROBLES, Mayra Judith; REVELES HERNANDEZ, Gabriela; MUNOZ ESCOBEDO, José Jesús  e  MORENO GARCIA, María Alejandra. Utility of albendazole/quinfamide in the treatment of intestinal phase of infection in murine model Trichinella Spiralis. AVFT [online]. 2012, vol.31, n.3, pp.51-55. ISSN 0798-0264.

Trichinellosis is a parasitic disease caused by the nematode Trichinella spiralis. Currently the treatment for Trichinellosis includes the administration of albendazole or mebendazole. These drugs are effective against the parasite, only if administered for prolonged periods; however there is a drawback that can cause adverse effects on the host. The aim of this study was to evaluate the therapeutic efficacy OXAL^® (albendazole /quinfamide) against infection by T. spiralis in mice during the intestinal phase of the infection (1, and 7 days) for a period of 3 days. The results showed that administration of OXAL^® for 3 days, had effective therapy for intestinal phase, since there was no parasitic load in the group with 1 day of infection, and the obtained in the group with 7 days of infection showed a significant decrease with regard to control, p <0.05.

Palavras-chave : Trichinella spiralis; intestinal phase; treatment.