Resumo

DAVILA, Carmen; ROJAS, Joselyn  e  BERMUDEZ, Valmore. Precocious central puberty secondary to hypothalamic hamartoma. AVFT [online]. 2014, vol.33, n.3, pp.79-83. ISSN 0798-0264.

Precocious puberty is defined as the sequential presentation of (in the configuration of the breast and pubic hair) pubertal changes before age 8 in girls, being influenced by several factors such as ethnic, nutritional, environmental, geographical. Its pathogenesis may be centrally (gonadotropin-dependent), at the peripheral level (not dependent on gonadotropins) or may be partial (variants of pubertal development). The highest incidence is observed in girls with a 10:1 ratio. In the presented case is suspected of PPC caused by CNS tumors the first thing to be discarded is the Hypothalamic Hamartoma, a congenital tumor of the nervous tissue of the hypothalamus; whose incidence in is 16% of cases and in males 50%. The role of MRI imaging for diagnosis is invaluable, concomitant with the determination of the LH surge in response to LHRH stimulation. The importance of the diagnosis lies in the need to initiate treatment; in the HH can be surgical or GnRH analogues; in such a way that part psychosocial and the final size of the patient can not be affected.

Palavras-chave : puberty early; dependent on GNH; hypothalamic Hamartoma.