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Archivos Venezolanos de Farmacología y Terapéutica

versão impressa ISSN 0798-0264

Resumo

MOLINA, Valentín et al. Therapeutic utility of the tumor segmentation process, applied to PET-CT images. AVFT [online]. 2016, vol.35, n.3, pp.66-70. ISSN 0798-0264.

In this work findings derived from the application of radiotherapy and chemotherapy, in a patient with tumors, are identified. The tumors require of segmentation and quantification process before and after those therapies. In order to obtain the morphology of such tumors and their volumes, a computational technique used in 3D images of positron emission tomography (PET) fused with computed tomography (CT), belonging to a pediatric patient diagnosed with non-Hodgkin lymphoma (NHL), is proposed. The proposed technique is divided into two stages: pre-processing and segmentation. The pre-processing is based on the application of a filtering process based on global enhancement similarity (GSE) to raise the quality of the information in the images. For tumors segmentation a technique based on region growing is considered. The NHL volumes derived from segmentation, are useful for both clinical monitoring lymphoma and analysis of therapeutic procedure.

Palavras-chave : Non-Hodgkin’s Lymphoma; PET-CT; Global Similarity Enhancement; Region Growing; Radiotherapy; Chemotherapy.

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