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Archivos Venezolanos de Farmacología y Terapéutica
versión impresa ISSN 0798-0264
Resumen
VELAZQUEZ DE CAMPOS, Omaira. Evidence for the combined use of meloxicam - esomeprazole. AVFT [online]. 2017, vol.36, n.1, pp.26-32. ISSN 0798-0264.
The nonsteroidal anti-inflammatory drugs (NSAIDS) are a class of compounds with anti-inflammatory, analgesic and antipyretic properties. They are some of the most used drugs in all age groups and for multiple indications, mainly musculoskeletal disorders and other painful processes in both acute form as in chronic form. In spite of its recognized effectiveness, NSAIDS have the potential to cause adverse reactions, especially related to the digestive system (GI) and kidney. To minimize the possibility of adverse GI effects with the use of NSAIDS, has suggested the concomitant use of drugs protectors of the gastric mucosa. Among these drugs, the most used are the proton pump inhibitors (PPI). Recently it has advocated the use of the fixed combination tablets (TCF), which have a number of advantages, including improved compliance with the therapy. In this review, we discuss the use of a TCF for esomeprazole and meloxicam.
Palabras clave : Meloxicam; esomeprazole; fixed combination tablets.