Abstract

FERNANDEZ, B et al. Efectividad de la Indometacina en el cierre del Conducto Arterioso Persistente en recién nacidos Pretérmino de la Maternidad "Concepción Palacios". RFM [online]. 2003, vol.26, n.2, pp.116-119. ISSN 0798-0469.

ABSTRACT: Objective: Determine the effectiveness of indomethacin in the closure of the ductus arteriosus in preterm newborn. Methods: It was made a prospective, descriptive and comparative study in 90 premature newborn with patent ductus arteriosus who received indomethacin between January, 1996 and December 1999. Each cycle consisted of three doses of indomethacin. Place: Maternidad "Concepción Palacios". Results: All patients had sepsis, 83.3% anemia, 71.1% metabolic upheavals, 68.9% metabolic acidosis, 43.3% hemodinamic alterations, 34.4% water overload and 11.1% barotrauma. Sixty newborn (66,7%) required one indomethacin cycle in order to the ductus closure. Childhood with anemia, hypervolemia and/or barotrauma needed more indomethacin cycles. Conclusion: The indometacin had 66,7% of effectiveness for the closure of ductus arteriosus.

Keywords : Newborn; Premature; Ductus arteriosus; Indomethacin; Effectiveness.