Resumo

EXPOSITO, CL. El Cannabis en la práctica Clínica. RFM [online]. 2003, vol.26, n.2, pp.127-130. ISSN 0798-0469.

ABSTRACT: Marijuana has been widely used for hundreds of years, it is perhaps one of the most popular drug of abuse. It has a long medical history, Cannabis, its preparations, derivates and similar synthetic prepartions are use to relieve symtoms associated with some medical conditions, such as: to relief nauseas and vomiting associate with cancer and AIDS therapies; for the relief of muscle pain and spasms; to help reduce the frequency of epileptic seizures; to lower intra ocular pressure in Glaucoma; to stimulate appetite and produce weight gain in AIDS and cancer patients. There are two commercially available drug products related to marijuana: dronabinol (MARINOL^®) and nabilone (CESAMET^®). Cannabinoids receptors CB1 and CB2, and some endogenous ligands named anandamide, 2-araquinoilglicerol, homo-g -linolenil etanolamine and palmitoiletanolamine, have been identified in brain.

Palavras-chave : Cannabis; Medical conditions; Receptors; Endogenous ligand; Dronabinol; Nabilone.