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vol.31 issue1Insuficiencia mitral isquémica: aspectos fisiopatológicos y terapéuticosEstudio cienciométrico de los trabajos de especialización: Facultad de Medicina. Universidad Central de Venezuela author indexsubject indexarticles search
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Revista de la Facultad de Medicina

Print version ISSN 0798-0469

Abstract

CORDERO, Raimundo E et al. Biomarcadores séricos del estado de salud en jóvenes universitarios de acuerdo a su nivel de actividad física. RFM [online]. 2008, vol.31, n.1, pp.29-36. ISSN 0798-0469.

The main objective of this study was to categorize the risk of suffering of cardiometabolic disease. For this, lipids and proteins metabolic biomarkers were used on sporting or sedentary students from Universidad Central de Venezuela. The following parameters were determined by colorimetric methods: Creatinine (Cr), Total protein (Tp), Albumin (Al), Triglycerides (Tg), Total cholesterol (T-Cho) and High density lipoproteins (HDL-C). The low density lipoproteins (LDL-C) were calculated by using the Friedewald formulae and globulins values were obtained by subtracting Tp from Al. The seric biomarkers levels were in the normal reference ranges. There were not significant differences on the HDL-C and globulins values between sporting and sedentary students. The sporting group showed very low Tg levels, with high T-Cho, due mainly to LDL-C. In this group, the conditions of the different components of the lipidic profile and T-Cho/HDL-C rate were influenced by a transitory lipemic distortion, possibly due to inflammatory mechanism mediated by immune response, which is observed in physical activity of high intensity. Low levels of HDL-C were obtained from both studied groups. Only 2,1 % from the sedentary group and 1,0 % of total sample showed low levels of albumin, which is associated to high risk of suffering from cardiovascular disease. Only a small part of the evaluated sample could be susceptible of suffering cardiometabolic disease.

Keywords : Lipidic profile; Cardiometabolic disease; Biomarkers; Physic activity; University students.

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