Abstract

NAVARRO, Pedro et al. Leishmaniosis tegumentaria americana: Efectividad del antimoniato de meglumina en series terapéuticas de 10 días. RFM [online]. 2009, vol.32, n.2, pp.101-106. ISSN 0798-0469.

American tegumentary leishmaniasis (ATL) is a health problem in the rural areas of Venezuela. Patients are referred to the Tropical Medicine Department (UCV) and to the University Hospital of Caracas with presumptive diagnosis of the disease, are studied to confirm the diagnosis and treated with antimoniate of meglumine in 10 days course at dose of 3 000 mg./day to 4 500 mg./day according to complications as outpatients or hospitalized. We report the results of 221 patients treated, mostly male adults from the rural area of the Miranda state with a sole ulcer in the limbs. Among the clinical presentation the cutaneous-localized form was predominating, followed by the localized muco-cutaneous with 4 and cutaneous-diffuse variety with 3. They responded with healing of the ulcers and disappearance of skin nodules, except one (0.3 %) who required anfotericine B due to lack of response to meglumine therapy. In this investigation there was the participation of students from the Tropical Medicine course: learning based on periodic publications with students.

Keywords : Leishmaniosis; Pentavalent antimonials; American tegumentary leishmaniosis; Muco-cutaneous leishmaniosis.