Abstract

RODRIGUEZ, Maritza et al. Respiratory capacity, vitamin C and malonilaldehyde levels in smokers and non smokers students of bioanalysis. INHRR [online]. 2010, vol.41, n.1, pp.7-13. ISSN 0798-0477.

Several authors have shown the implications of smoking in the alteration of respiratory capacity and oxidation / antioxidation system and the importance of screening them for help in preventing various diseases. In the present investigation was to assess respiratory capacity and vitamin C (VC) and malondialdehyde (MDA) levels of smokers and non smokers. Partici - pated 50 bioanalysis students both sexes, classified by the World Health Organization in daily smokers (DF), occasional smokers (OF) and non-smokers (NF). The evaluated parameters were: forced expiratory volume in first second (FEV₁) and forced vital capacity (FVC), levels of VC and malonilaldehyde. Results presented as X ± SD and percentages and statistically analyzed by ANOVA, were 69,2% and 84,6% of students (DF, OF) had normal values of FVC and FEV, respectively, without differences significant height. VC levels (mg/dl) Were 1.19 ± 0.30 (NF) with 1.12 ± 0.09 (OF) without significant differences between them and the MDA (ìm/l) showed a statistically significant increase (p<0.05) their values in OF (1.56 ± 0.5) with res pect to NF (0.99 ± 0.60). We conclude that the values of MDA showed a significant increase in OF, which correspond to manifestations of oxidative stress. However, vitamin C levels, though were lower in FO group, showed no significant differences as well as spirometry

Keywords : Smoking; respiratory capacity; malonildehyde; lipid peroxidation; vitamin C; spirometry.