Resumen

DI BERNARDO, María L et al. Study of serum levels of copper and zinc and its possible roll like indicators of primary dysmenorrheal . INHRR [online]. 2010, vol.41, n.2, pp.27-36. ISSN 0798-0477.

In this work has determined the copper content and zinc in sanguineous serum of women with primary dysmenorrheal diagnosed clinically and a group of women control with I diagnose negative for the studied pathology. The samples of sanguineous serum taken before (a) and during (d) the second day of the menstruation come from 39 women in ages between 17 and 21 years of age, n = 14 controls and n = 25 women with primary dysmenorrheal. They were processed by Spectroscopy of Atomic Absorption with injection in con-tinuous flow (EAA-IFC). The concentrations obtained of 1.56± 0.43 mgL^-1 of copper and 1.28± 0.34 mgL^-1 of zinc before menstruation and 1.06 ±0.23 mgL^-1 of copper and 1.21 ±0.4 mgL^-1 of zinc during the menstruation (second day), for the group control and 1.64 ±0.52 mgL^-1 of copper and 1.88 ±0.61 mgL^-1 of zinc before menstruation and 1.21± 0.34 mgL^-1 of copper and 0.94± 0.27 mgL^-1 of zinc during the menstruation in the group study. In relation to the serum levels it initiates to them in both groups were not significant differences (p = 0.63). The zinc, observe he himself behavior, between both groups before the menstruation was not observed significant differences with p = 0.16, nevertheless, during the menstruation I throw p = 0.0033. This result evi-dence that indeed the copper is affected by the alteration of the prostaglandins, being probably one of the people in charge of the annoyances that appear in this pa hologyt and other indirect effect motivated by the abrupt reduction of the zinc, such as alteration in the synthesis and excretion of the hormone stimulating follicle (FSH), of the luteinizante hormone (LH), abnormal development of the ovary, alterations of the menstrual cycle. The copper/zinc re ationl I calculate both groups, with values of 1.47 and 1,06 before and during res pectively for the group control and the group under study 1,36 and 1.97 before and during respectively.

Palabras clave : Copper; zinc; primary dysmenorrheal; copper/-zinc relation; atomic absorption.