Abstract

FIGUEREDO D, Cyndy L; CAMPERO R, Joseph G; CORREA, Doryanna  and  TORRES, Luis C. Susceptibility Ceftaroline in methicillin-resistant Staphylococcus aureus. INHRR [online]. 2016, vol.47, n.1-2, pp.61-75. ISSN 0798-0477.

Ceftaroline is an antibiotic of last generation cephalosporins subgroup. Is the first marketed beta-lactam having activity against Methicillin-resistant         S. aureus (MRSA). The aim of this study was to describe the pattern of susceptibility to ceftaroline in MRSA isolated in the Microbiology Laboratory of Hospital Vargas of Caracas. Methods: Isolation and identification of the strains was performed by conventional biochemical tests and susceptibility testing by disk diffusion method according to CLSI 2015. Results: A total of 100 MRSA strains were analyzed, of which 100% he was sensitive to ceftaroline (≥ 24 mm), with a range of 26-35 mm, not detected any intermediate or resistant strain. Conclusion: Ceftaroline shows excellent in vitro activity against MRSA, so it could be presented as a promising alternative in the treatment of infections caused by this organism.

Keywords : S. aureus; methicillin-resistant; Ceftaroline; antibiotic; betalactamic.