Resumo

PENA SEVILLA, Lourdes et al. Tumor neuroectodérmico primitivo de maxilar: Presentación de un caso. Rev. venez. oncol. [online]. 2006, vol.18, n.4, pp.250-258. ISSN 0798-0582.

Periferical neroectodermic primary tumor is a part of the sarcoma Ewing family and represents 5 % of them. The superior maxillary location is not frequent, we report these clinical case of a male teenage of 15 years old sent to our hospital with loss weigh, tumor in the oral cavity in the left superior quadrant of the oral cavity, with a diameter of 6 cm, that it occupies 50 % of the same one with sobreinfection, with necrosis. The biopsy reported: tumor of undifferentiated round cells. We observed a growth of the tumor that triples its size in 8 days, it occupies it in totality, with tendency to obstruction of the air way, needed emergency traqueostomy and gastrostomy. The inmunohistoquimical studies reveal primary neuroectodermic tumor (inmunoreactive to CD99 enolasa neurospecific and cromagine), received two cycles of ciclofosfamide, vincristine, actinomicyn D, ifosfamida and etoposid, with disease progression and depletory of his physical status; receive radiation therapy 6 000 cGy with platinum, obtaining favorable condition to surgery: A bilateral maxilectomy with preservation of the floor of the orbit. The anatomopathological study report fibromixoide weave a lot of vascularization without evidence of malignity, free margins. Actually, 7 months without evidence of disease waiting for platinum prosthesis to restituted the functional deglution. In the inusual localizations, the treatment has to be multidisciplinary, individualized, and include the three treatment modalities (Quemotherapy, radiation therapy and surgery).

Palavras-chave : Cancer; primary neuroectodermic tumor; oral cavity; maxillary; treatment; surgery; quemotherapy; radiation therapy.