Abstract

MIJARES BRINEZ, Alirio et al. Tipificación del virus de Papiloma humano relación con el carcinoma de cavidad oral. Rev. venez. oncol. [online]. 2007, vol.19, n.4, pp.321-331. ISSN 0798-0582.

OBJECTIVES: The purpose of this work is to evaluate the relationship of the human papilloma virus and the pathogenesis of the tumours of the oral cavity, and demonstrated his presence and other cofactors should be the causing this pathology and his influence in the prognostic factors of these type of pathology. METHODS: Realized a retrospective work in the Padre Machado Oncology Hospital, Head and Neck Service and in La Floresta Medical Institute. Caracas, Venezuela of the paraffin blocs of 72 patients seen between the years 1996 and 2005 we utilized a descriptive statistics to resume and to obtained dates and to estimate the proportions, and utilized the confidential binomial and the Kruskal-Willis test. RESULTS: The increment of the epidemic evidences and molecular studies demonstrated the strong existent relationship between the human papilloma virus and the oral cavity carcinoma, in this study shown this relation in than half hundred of samples taken from lives December 1996 to November 2003, and the relation between different cofactors added how are the tobacco and alcohol consumer, it influences in the presage of this lesions and his aggressive comported. CONCLUSIONS: We have enough epidemic data, to settle down that in an important percentage of the patients that present lesions related with the human papilloma virus, prevailing the identification of the number 16, added to habits like the tobacco and alcohol produce a bad influence in the prognostic of these lesions when their factors is combined.

Keywords : HPV; Head; neck; squamous cell; carcinoma.