Resumen

SEPULVEDA, Mauricio; CONTRERAS, Eduardo  y  MARTINEZ, Nataly. Enfermedad de Castleman descrìpción de un caso Clínico. Rev. venez. oncol. [online]. 2008, vol.20, n.2, pp.104-107. ISSN 0798-0582.

The Castleman’s disease is a rare disorder characterized for a benign growth and that may develop in the lymph node tissue throughout the body. Most often, they occur in the chest, the stomach, and in the neck. Less common sites include the axils, the pelvis, and the pancreas. Usually the growths represent an abnormal enlargement of the lymphatic’s nodes normally found in these areas. There are two main types of Castleman’s disease: The hyaline vascular type and the plasma cell type. The hyaline vascular type accounts for approximately the 90 % of all the cases. Most of the individuals exhibit no symptoms of this form of the disorder or they may develop non cancerous growths in the lymphatic nodes. The plasma cell type of Castleman’s disease may be associated with fever, weight loss, skin rash, early destruction of the red blood cells, leading to unusually hemolytic anemia, and or hypergammaglobulinemia.

Palabras clave : Castleman; hyaline; vascular; plasma cell.