Resumo

ALVARE Z FLORES, CAROLINA et al. Diferencias en Parámetros Nutricionales pacientes con Tumor de ovario Maligno vs. Benigno. Rev. venez. oncol. [online]. 2008, vol.20, n.3, pp.130-136. ISSN 0798-0582.

according to their stripes malignancy in benign or malign, in order to suggest a diagnostic test previous to the histopathology study. METHODS: We conducted a transversal study in which we evaluated patients with ovarian tumor diagnosis by an anthropometric form: Weight, height, skin folds, and the functional (Karnofsky scale), also the biochemical: Albumin, transferrin, total protein, hemoglobine, hematocrite, total lymphocyte count and the CA-125. After the histopathology analysis, the patients were classified according to their tumor’s malignancy, in order to compare the results between the two groups with a Mann-Whitney U test. RESULTS: We assessed 58 patients: 35 with benign tumor and 23, malignant. We found significant differences in albumin, transferrin and the tumor marker CA-125. For these indicators, we constructed the ROC curves, and finding (with a specificity mayor of 80 %) the possibility of associating the transferrin to the tumors’ malignancy. CONCLUSION: The patients with a malignant ovarian tumor present an increased tendency to the malnutrition, comparing with patients whose tumor is benign. The body composition wasn’t significant in this study’s results, but we recommend using more accurate methods how the DEXA. No diagnostic test was determined, but we found an evidence of the biochemical markers associated to the malignancy of the tumor.

Palavras-chave : Tumor; ovarian; anthropometric indicators; biochemical indicators; diagnostic; test.