Resumo

FERNANDEZ, Anyelin et al. Metástasis óseas en adenocarcinoma de mama. Rev. venez. oncol. [online]. 2008, vol.20, n.4, pp.181-185. ISSN 0798-0582.

OBJECTIVE: Bone metastasis still represents one of the main complications of breast cancer during the follow up of these patients. The objective of the current series was to determine the prevalence of bone metastasis in patients diagnosed of breast adenocarcinoma at our center, the location and number of lesions, treatment selected and the overall patient survival. METHODS: A retrospective study of a group of female patients with a diagnosis of breast adenocarcinoma and bone metastasis was carried out during a ten year period, between the years 1996 and 2005. Medical charts of 1 610 women were analyzed. RESULTS: We found 200 cases with bone metastases, 90 % were diagnosed by bone scans. The ages of these patients ranged between 41 and 50 years. Metastatic bone disease was multiple in 55 % of cases. All the patients received radiotherapy treatment. The main location of the bone lesions was the spine, accounting for 33 % of all cases. Overall survival was one year in this group. CONCLUSIONS: Bone metastasis is a frequent clinical finding in the setting of breast adenocarcinoma. Prognosis is dismal and it is corroborated when we compare our results to those reported in the literature.

Palavras-chave : Adenocarcinoma; breast; bone metastasis; survival.