Resumen

ZENZOLA, Víctor et al. Uso del ganglio centinela con azul patente y radiofármaco en pacientes con cáncer de endometrio. Rev. venez. oncol. [online]. 2009, vol.21, n.1, pp.3-10. ISSN 0798-0582.

OBJECTIVE: The purpose of the present study was to assess the feasibility of intraoperative sentinel node detection based on the combined use of radio colloid and patent blue labelling in patients with diagnosis of endometrial cancer. METHODS: Fourteen patients with endometrial cancer classified of stage I underwent a sentinel nodes procedure based on combined technetium 99 labelled colloid and patent blue injected pericervically. After the sentinel nodes procedure, all patients underwent abdominal hysterectomy, bilateral salpingo-oophorectomy, and complete pelvic lymphadenectomy. RESULTS: The sentinel nodes were identified in 10 of the 14 patients (71.4 %). Metastases were detected in: One sentinel node of a patient with an endometrioide adenocarcinoma, seeming stage IB G3, by haematoxylin and eosin staining. No more than one sentinel node was detected in each patient. All were in the pelvic localised. No false negative sentinel node results were observed. CONCLUSION: Obtain of sentinel node procedure based on combination of radio colloid and patent blue injected pericervically is feasible in patients with diagnosis of early endometrial cancer. The rest of pelvic ganglions were 100 % predictable. This technique reflect the true ganglion status, avoiding an unnecessary pelvic lymphadenectomy.

Palabras clave : Sentinel node biopsy; endometrial cancer; radio colloid.