Abstract

BRAVO BELLO, Yris et al. Tumor de células granulares de la mama: Reporte de un caso. Rev. venez. oncol. [online]. 2009, vol.21, n.1, pp.40-45. ISSN 0798-0582.

OBJECTIVE: The objective of this work is to report a granular cells breast tumor case, generally benign neoplasia, of Schwann cells origin that often simulates a breast carcinoma. METHODS: Description of a clinical case and literature revision. RESULTS: A 33 years old female patient, with right breast nodule attended to a mastology evaluation, which was concluded class V (Highly suspicious lesion). And ultrasound guided core biopsy was done. The pathology report was breast fibroadenoma. Due to the disagreement of the results with the suspicious images, she was offered with image guided right partial mastectomy plus preoperative frozen section which was report negative for malignancy. The definitive biopsy: Granular cells Breast Tumor. Immunohistochemical: Positive immunoreactivity in the tumor cells with protein S100 and enolase neuronal specific. CONCLUSIONS: 1. Granular cells breast tumors are not a frequent entity. Although is benign, it clinically and radiological simulates a breast carcinoma. 2. Histogenesis of granular cells breast tumor continues in discussion. 3. The tumor in general is benign and solitary, but it can recur and experiment malignant conversion (unusual but possible and published), for this reasons the patients should be strictly followed up.

Keywords : Breast; cancer; granular cells; tumor; benign.