Resumen

ACOSTA F, Víctor et al. Carcinoma ductal IN SITU de la mama: primeros 100 casos ceclines. Rev. venez. oncol. [online]. 2010, vol.22, n.2, pp.88-93. ISSN 0798-0582.

OBJECTIVES: Describe first 100 cases of ductal carcinoma in situ in our institution. METHODS: 100 cases treated adopted the definition of mic by Silver and Tavassoli: 77 pure and 23 mic. 69 % we performed breast conserving surgery 31 % total mastectomy 24 % reconstruction, 1 was bilateral, 7 % without reconstruction. 64 % received complementary radiotherapy. 36 % treatment was surgery alone. 77 % recieved hormonal adjuvant therapy. 46 % we performed sentinel lymph node biopsy: 25 % were pure and 21 % mic. RESULTS: 83 % initial form of presentation was micro calcifications. The histological type was cribiform and mixed (75 %). The mammographic and histological size matched 20 mm average. 87 % were nuclear grade II and III, 82 % of the mitotic activity was moderate or low only 4 % were high. 78 % had necrosis. Out of the 25 patients with pure in which we practice none presented ganglion disease and out of the 21 patients with mic, 9.52.% presented ganglion metastasis. 2 % had local recurrence, both of them with invasive disease, one 52 months the other one at 58 month from surgery. One didn´t received radiation. Both were treated with rescue mastectomy. There was no death diseases related. CONCLUSION: Adequate and good management of cases results related to disease free survival and overall survival. We can classify sub group of patients in which may avoid radiation without increasing the risk of mortality.

Palabras clave : Cancer; breast; in situ; surgery; radiation therapy; adjuvant; super life.