Abstract

AGUILAR, Daysi et al. Carcinoma de mama triple negativo experiencia en instituto de oncología “Dr. Miguel Pérez Carreño”. Rev. venez. oncol. [online]. 2011, vol.23, n.4, pp.246-249. ISSN 0798-0582.

OBJECTIVE: Presenting the experience of our institution in the treatment of negative triple breast carcinoma and assess their behavior. METHODS: Is a retrospective and descriptive study. We evaluating 998 stories of patients with a diagnosis of breast carcinoma that attended the Institute of Oncology “Dr. Miguel Perez Carreño” from 2000 to 2004, selecting patient’s negative triple, tracking them until December 2009. RESULTS: We are reviewed a total of 998 medical histories of patients with a diagnosis of breast carcinoma in a period of four years (2000-2004). 940 had immunohistochemistry which 53 (6 %) were triple negative review. The average age was 48.3. Histological type frequent was ductal adenocarcinoma infiltrating 47 (88.%) patients. Stage IIB was 42 (43 %) cases. Neoadyuvancia apply in 45 (83 %) patient. Treatment with CAF 45 was (83 %); AC 6 (11 %); CMF chemotherapy schemas 3 (6 %). Were 35 (65 %) MT+VAI-II and 01 MPO cases found. 48 (90 %) patients receiving adyuvancia, 35 (66%) were they apply chemotherapy and radiation therapy. Budget free of disease 34 (64 %) patients with interval longer disease free 49 months 15 (44 %) cases. Submitted 10 relapse (19.%) cases. Increased frequency of relapse was the bone 03 (30.%). CONCLUSION: Consideration of in order to obtain immunohistochemistry a more precise classification and thus identify each patient to provide more effective, with a view to increasing disease-free interval treatment should be and thus the survival overall

Keywords : Cancer; breast; classification; immunohistochemistry; treatment; disease-free range.