Resumo

ZABALA, Norielis  e  HANN AOUI, Erika. Comparisonplatelet count, singdifferentmethodologies,in patients withthrombocytopenic purpura and myelodysplastic syndromes. Saber [online]. 2013, vol.25, n.3, pp.259-264. ISSN 1315-0162.

Platelet count was assessed in three groups of patients, according to the manual method of Brecher and Cronkite and the automated hematology analyzers using different principles: Swelab ALFA (impedance), Celldyn 3200 (flow cytometry) and Beckman Coulter LH 500 (volumetric impedance, radio frequency and laser light scattering). The patients with thrombocytopenic purpura (PT) and myelodisplastic syndromes (MDS), came from the hematology consultation at University Hospital “Antonio Patricio de Alcalá”, Cumana. For that purpose, blood samples were taken from patients of both sexes, aged between15 and 50 years, and diagnosed with these diseases. In addition, 20 individuals were taken from the consultation above, without alterations in the number of platelets, as control group. The results were subjected to analysis of variance and correlation at 95% confidence, throwing significant differences in patients with PT and SMD, both from the manual method and by the various automated procedures (p <0.05) and a positive correlation; whereas in the control group no significant differences were obtained (p > 0.05). Taking into account the results obtained, it can be considered as valid the counts made by the various methods under study, both, for patients with a number of platelet within refence values, as well as below it.

Palavras-chave : Thrombocytopenic; purpura; myelodysplasticsyndromes; platelet count.

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