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BRUZUAL VILLARROEL, Hellen Yandri; HENRIQUEZ GUZMAN, Willian; CRESCENTE, Oscar  e  LANZA, José Gregorio. Essential oil of Wedelia calycina (ASTERACEAE): chemical composition, antibacterial and antifugal activities. Saber [online]. 2015, vol.27, n.1, pp.87-93. ISSN 1315-0162.

Essential oil of Wedelia calycina L.C. Rich was investigated for its antibacterial and antifungal activities. The essential oil was obtained by drag through steam distillation of leaves with a yield of 0.025 %. It was analyzed by gas chromatography-mass spectrometry (GC-MS). Fourty four compounds were identified, the main ones being germacrene D (8.83%), 3,3,7,7-tetramethyl-5-(2-methyl-1-propenyl)-triciclo[4.1.0.0(2,4)] heptane (8.66%), β-sesquiphellandrene (7.87%), oxide of caryophyllene (5.10%) and 1,4-methaneazulen-7(1H)-ona,octahydro- 4,8,8,9-tetramethyl-, (+) (4.65). Sesquiterpenes hydrocarbons (44.83%) and oxygenated sesquiterpenes (26.90%) were the predominant groups of compounds. The dominant groups were sesquiterpene hydrocarbon (44.83%) and oxygenated (26.90%) compounds followed by monoterpenoid compounds (15.79%) and the remaining 12.41% were aliphatic low molecular mass compounds. Wedelia calycina essential oil exhibited moderate antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus and Klebsiella pneumonia; showed a linear dose response against Bacillus subtilis, and no activity against Escherichia coli and Enterococcus faecalis. The essential oil showed no activity against the tested pathogenic or fito-pathogenic fungi.

Palavras-chave : Volatile components; sesquiterpenes; germacrene D; biological activity.

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