Saber
versão On-line ISSN 2343-6468
Resumo
WAHAB-EL-FATAIRI, Fadi et al. Pneumocystosis in the internal medicine service, university hospital complex Dr. Luis Razetti, Barcelona, Venezuela, 2011-2012. Saber [online]. 2015, vol.27, n.3, pp.406-413. ISSN 2343-6468.
In Venezuela and in the state Anzoátegui, the pneumocystosis, is little studied. To weigh that it is an infection opportunist caused by Pneumocystis jirovecii, it causes pneumonia of high morbility and mortality. The inmunocompromised patient is those that present bigger risks of acquiring this infection. The objectives of this investigation were to determine the infection frequency for P. jirovecii in patient with breathing symptoms and immunocompromised hospitalized in the Service of Internal Medicine of the Complex Hospital University “Dr. Luis Razetti", and to describe the clinical parameters, of laboratory, radiological and epidemic. To increase the sensibility of the diagnosis etiologic of the pneumocystosis you employment the combination of microscopic methods (Giemsa and direct immunofluorescence technique). 52 samples of spontaneous sputum were studied, which were processed by fluidification -concentration. Results: 8 patients (15.38%) they were positive. The most frequent clinical manifestations among the patients with pneumocystosis were the dyspnea (75%), cough (62%) and bullous (50%) they were the most common signs among those infected, the one infiltrated alveolar (62.5%) and the spill pleural (37.5%) they prevailed as radiological signs. Was the LDH presented in values 300 UI/L in 5 of the positive patients. Other common discoveries were: moderate anemia and breathing alkalosis. The evaluated epidemic aspects were the gender, occupation, smoking, accumulation and comorbidities, in this last aspect, the diabetes, hypertension and infection for the VIH was opposing comorbidities among these patients. The confirmation of the infection in the state Anzoátegui, demonstrates that in this hospital the agent exists and probably you this underdiagnosticated the pneumocystosis.
Palavras-chave : Pneumocystis jirovecii; immunofluorescence direct; VIH; immunosuppression; Anzoátegui.