Resumo

GUTIERREZ, Clara Nancy; PEREZ YABARRA, Luis  e  AGRELA, Irma Fatima. CANINE EHRLICHIOSIS. Saber [online]. 2016, vol.28, n.4, pp.641-665. ISSN 1315-0162.

Canine  ehrlichiosis  is  an  emerging  infectious  disease  transmitted  by  ticks,  caused  by  Ehrlichia  spp.(Proteobacteria: Ricketsiales), which affects members of the family Canidae. The etiological agents are Gram-negative,  obligate  intracellular,  rounded,  and  pleomorphic  bacteria,  the  latter  especially  in  cell cultures. These bacteria are localized in vacuoles surrounded by membranes (morulae) in the blood cells cytoplasm, and depending on the species, have a tropism for lymphocytes, monocytes and granulocytes. Historically  the  disease  is  endemic  to  tropical  and  subtropical  regions,  but  is  reported  increasingly  in temperate climate regions. This can be attributed to several factors, which include the improvement in diagnostic  tools,  environmental  and  climate  change  (global  warming)  that  directly  influence  the distribution of ticks, and the large number of travels with pets from one place to another in the planet, which has contributed to the establishment of this disease in non-endemic areas. Co-infection with other tick-borne pathogens is common and this complicates the pathogenesis, clinical manifestations, diagnosis and  treatment.  Often,  the  pathogen  cannot  be  completely  eliminated  despite  antibiotic  therapy  and resolution of clinical signs. Currently, there is no vaccine available, making the use of ectoparaticide to be a good choice for the prevention of the disease. This disease is a problem in veterinary medicine and zoonotic potential of these agents is a consideration of great importance to human health.

Palavras-chave : Ehrlichia canis; Ehrlichia ewingii; Ehrlichia chaffeensis; dog; ehrlichia; zoonosis; rickettsia.

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