Abstract

LEMUS-ESPINOZA, DRUVIC; VILLARROEL JIMENEZ, OSKARINA  and  MANISCALCHI BADAOUI, MARÍA TERESA. Candida spp. ISOLATED FROM PATIENTS WITH VULVOVAGINITIS OF RURAL COMMUNITIES FROM CARIPE MUNICIPALITY, MONAGAS STATE, VENEZUELA, 2014. Saber [online]. 2016, vol.28, n.4, pp.720-725. ISSN 1315-0162.

This study evaluated patients with symptomatic vaginal fungal infection in a rural area of Caripe Municipality, Monagas  state,  Venezuela,  aiming  to  identify  the  species  involved  and  their  sensibility  to  antimicotics. Identification of species of Candida yeast was made with the use of CHROMagar Candida® and API AUX 20®. Additionally, in vitro susceptibility to fluconazole was evaluated by the agar diffusion method (CLSI, M44-A2). The prevalence of vaginal candidiasis was 23/86 cases (26.7%) among women 15 to 60 years. Candida albicans was the most common species among patients (39.1%). However, other isolated agents within the same genus Candida dominated (65.2%) and were identified: Complex C. glabrata (4/23; 17.4%), C. tropicalis (4/23; 17.4%), Complex C. parapsilosis (3/23; 13.1%), C.guilliermondii (2/23; 8.7%), C. krusei (1/23; 4.3%) and one episode of  mixed  infection  with  C.  albicans  and  C.  krusei  (1/23).  No  statistical  difference  was  observed  between symptoms;  vulvovaginal  erythema  occurred  in  all  infected  women.  More  than  half  of  the  yeasts  (15/23)  were sensitive  to  fluconazole.  In  this  population  sample,  isolates  of  C.  albicans  and  C.  guilliermondii  were  100% sensitive to fluconazole, while the  C. krusei strain (1/23) isolated from a  mixed infection was resistant to this antimicotic.  Other  species,  like  C.  tropicalis  (4/23),  C.  glabrata  (2/23)  and  Complex  C.  parapsilosis  (1/23) showed dose-dependent susceptibility to fluconazole. In gynecological evaluations of patients from rural or urban communities, with clinical picture of micotic vulvovaginitis, a microbiological study of vaginal secretions should be implemented.

Keywords : Candida spp; Candida albicans; vaginal candidosis; fluconazole.

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