Abstract

BRITO, A et al. Resistencia de Serratia marcescens a los antimicrobianos en Venezuela. Rev. Soc. Ven. Microbiol. [online]. 2000, vol.20, n.1, pp.01-01. ISSN 1315-2556.

Abstract We studied the resistance to antimicrobial agents of 659 strains of Serratia marcescens from the Survey Project Control of Resistance to antimicrobial agents in Venezuela during the period 1995 to 1998, following the agar diffusion method according to the NCCLS standards. Serratia marcescens showed a high percentage of resistance to ampicillin and ampicillin-sulbactam, 84-92% and 73-80% respectively; to piperacillin there was a much lower percentage (13-26%). To the third generation cephalosporins the resistance reported was as follows: ceftriaxone 20%, ceftazidime 15%, cefotaxime 23% and cefoperazone 16%. To cefepime, a fourthgeneration cephalosporin, there was reported a low percentage of resistance (6%). The resistance reported to gentamicin and amikacine is high (21 and 19%) respectively, and lower for tobramycin (11%). The resistance to quinolones is low, with values ranging from 2 to 5%. The higher percentage of resistance reported for third generation of cephalosporins it is due to the production of b-lactamases of expanded-spectrum

Keywords : Serratia marcescens; amikacina; Serratia marcescens; resistance to antimicrobial-agents; amikacine; third generation cephalosporins.