Resumen

SOSA BRICENO, M; CASTILLO COLOMBO, C  y  SCORZA, J. Inhibitory activity of Bacillus spp. against dermatophytes.. Rev. Soc. Ven. Microbiol. [online]. 2004, vol.24, n.1-2, pp.59-64. ISSN 1315-2556.

Samples of domestic animals excrement, coming from Trujillo State, were processed for sporulate bacteria isolation belonging to Bacillus gender, in order to assay them against dermatophytes and to determine their antifungal activity. A total of 52 strains of sporulate bacteria were isolated, which the biggest number was isolated in hens (19 strains), followed by goatishes (12 strains). In bovines, equines and porcines, 7 strains were isolated of each one of the samples. Of 60 patients, attended in the dermatology consulting "José Witremundo Torrealba" Investigations Centre, University Nucleus "Rafael Rangel", Andes University in Trujillo, to present different affections of the skin, 3 different species from dermatophytes were isolated: Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis. Of 52 strains of Bacillus gender isolated in our laboratory, 23% (12 strains) were active to inhibit T. mentagrophytes and T. rubrum growth. Against M. canis, 21% (11 isolated strains) showed inhibitory activity. We highlight that this antifungal activity takes place in relatively simple and economic culture media, which suggests the discovery of a new field of applied investigation.

Palabras clave : Bacillus; dermatophytes; inhibitory activity; thermostability; sporulate antifungal agents..