Abstract

NIEVES, Elsa  and  RONDON, Maritza. Survival of the Leishmania parasite in the vector insect:molecular interactions. Rev. Soc. Ven. Microbiol. [online]. 2007, vol.27, n.2, pp.66-72. ISSN 1315-2556.

Abstrac: Leishmania require two hosts to complete their life cycle, a vertebrate and a vector insect. Vector phlebotomies have been able to survive in co-existence with the Leishmania parasite. This co-existence has been reached due to the diverse defense strategies developed by the insect, which include innate immunity strategies. On the other hand, the survival of the parasite in the vector is due to complex evasion and co-evolution mechanisms. To recognize these Leishmania-vector interaction mechanisms and to further their molecular study can contribute to the development of targets for new strategies that reduce the vectorial capacity of Leishmania vector phlebotomies

Keywords : Leishmania; phlebotomies; survival; immune system.