Resumo

CERMENO, Julman Rosiris  e  HERNANDEZ DE CUESTA, Isabel. Cytomegalovirus (CMV) seroprevalence in patients infected with human immunodeficiency virus (HIV) at Bolivar State, Venezuela. Rev. Soc. Ven. Microbiol. [online]. 2012, vol.32, n.1, pp.70-74. ISSN 1315-2556.

Cytomegalovirus (CMV) is a pathogenic agent widely distributed in nature which can produce primary, latent, chronic and persistent infections. With the purpose of determining CMV seroprevalence in patients infected with human immunodeficiency virus and/or with acquired immunodeficiency syndrome at Bolivar State in Venezuela, we carried out a transversal section study where we detected anti-CMV IgG antibodies by an immunoenzymatic assay in 83 patients. None of the patients presented clinical findings indicating central nervous system infection. Of the 83 patients, 94% (n=78) showed anti-CMV IgG type antibodies, predominating in the 20-29 years group (n=28, 36.1%), and in male sex (n=42, 53.8%). A higher seroprevalence was demonstrated in patients with CD4+ lymphocyte counts between 100-200 cells/mm³. A statistically significant association between age increase and IgG-CMV antibody titers (p=0.009) was observed.. CMV infection has a high prevalence in human immunodeficiency virus infected patients at Bolivar State (Venezuela), which increases proportionally to age

Palavras-chave : cytomegalovirus; seroprevalence; acquired immunodeficiency syndrome; Venezuela; human immunodeficiency virus.

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