Abstract

CORREA RIVAS, Krismay Anais; BRAVO TORREALBA, María Vanessa; SILVA ALVARADO, Ricardo Alonso  and  MONTIEL, Marynes. Antibiotic susceptibility of Pseudomonas aeruginosa isolated from drinking water from Santa Rosa de Agua community, Maracaibo Zulia State. Rev. Soc. Ven. Microbiol. [online]. 2015, vol.35, n.2, pp.83-88. ISSN 1315-2556.

Pseudomonas aeruginosa is a group of ubiquitous bacteria found in the environment. Its high level of intrinsic antibiotic resistance, coupled with its ability to develop new mechanisms of resistance, make this opportunistic pathogen one of the most difficult to treat. The aim of this study was to evaluate the antibiotic susceptibility of P. aeruginosa isolated from drinking water from Santa Rosa de Agua community, Maracaibo, Zulia State, as well as the detection of antibiotic resistance enzymes. Forty isolates were analyzed using asparagine agar broth and cetrimide, with subsequent biochemical identification. Antibiotic susceptibility was determined by the disc diffusion method and enzyme production was studied by combined disc diffusion. Of the specimens studied 92.5% were positive for Pseudomonas, of which 22 isolates were P. aeruginosa. The highest percentage of resistant strains were to aztreonam (36.4%), followed by ceftazidime (22.7%), cefepime (13.6%) and tobramycin (4.5%). The determination for extended-spectrum beta-lactamases (ESBL) was 18% positive and 9% positive for carbapenemases (KPC) and metallo-beta-lactamases (MBL).

Keywords : Pseudomonas aeruginosa; susceptibility to antibiotics; drinking water; Santa Rosa de Agua.

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