Resumo

TORRES-CHATI, Jane; LEON-QUISPE, Jorge  e  TOMAS-CHOTA, Gloria. Antibacterial and antifungal activity from leaf extracts of Luma chequen (Molina) A. Gray “myrtle” against pathogens of clinical origin. Rev. Soc. Ven. Microbiol. [online]. 2017, vol.37, n.1, pp.10-16. ISSN 1315-2556.

In the present work we evaluated the antimicrobial activity of Luma chequen “myrtle” against reference strains, bacterial pathogens and yeasts isolated from blood cultures of a hospital facility. Luma leaves were harvested, macerated and obtained ethanol and aqueous extracts to be evaluated for their antimicrobial activity against laboratory of reference strains, bacterial pathogens and yeasts isolated from blood cultures of a hospital laboratory. The activity of the extracts was assessed by the modified method of diffusion in wells and determination of the minimum inhibitory concentration (MIC) by microdilution. It was determined that the ethanol extract of the plant presented greater inhibitory activity against the pathogens, being the most sensitive Staphylococcus aureus, S. epidermidis and Klebsiella pneumoniae at the MIC of 3.125 mg / mL and for Candida tropicalis and C. parapsilosis with a MIC of 1.56 mg / mL. It was concluded that Luma chequen, an ethnomedicinal plant native from Southern Peru, has bioactive components that inhibit human pathogens causing bacteremias and fungemias.

Palavras-chave : traditional medicine; phytotherapy; plant extracts; Luma chequen; antimicrobial activity; myrtle.

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