Abstract

MORA, Eddy Verónica et al. Clear cell condrosarcoma with neuroendocrine differentiation: Report of a case . Salus [online]. 2011, vol.15, n.2, pp.40-41. ISSN 1316-7138.

We described a case of skeletal clear-cell chondrosarcoma with neuroendocrine differentiation. Case: A male 56-year old patient with a mass in L1, L2, L3 vertebral body, with extension to the soft tissues, and metastasis to both lungs. Histologically, the tumor structure was a lobullated mass, with medium size clear cells and scanty extracelular chondroid matrix. Immunohistochemical studies showed positivity for S-100 protein, neuron specific enolasa and epithelial membrane antigen. Conclusions: Evidence of extraskeletal chondrosarcoma with neuroendocrine features was described. Here, we present a unique case of clear-cell chondrosarcoma with neuroendocrine features.

Keywords : hondrosarcoma; neuroendocrine features.

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