Resumo

YEGUEZ MARIN, Francisco A  e  CASTEJON, Olivar. Beta subunit of human chorionic gonadotropin, free testosterone and fetal sex in the development of preeclampsia. Salus [online]. 2012, vol.16, n.3, pp.008-012. ISSN 1316-7138.

The research aims to determine the relationship between levels of free testosterone (FT), beta subunit of human chorionic gonadotropin (β-hCG) and fetal sex with preeclampsia (PE). Were studied previous informed consent, 20 primiparous complicated with PE and 20 primiparous uncomplicated, at gestational age greater than 20 weeks, divided into 50% male fetuses and 50% female fetuses, determining the levels of β-hCG and Tl. The analysis reported that pregnant women with male and female fetuses without PE had significantly higher levels of β-hCG than those with PE and identical fetal sex, which differs from that reported in the literature. In pregnant not PE levels β-hCG were significantly higher than in pregnancies with fetal PE for both sexes. Pregnant women with male fetuses and PE reported higher levels of Tl that pregnant women without PE and identical fetal sex, similar to that reported in the literature. In pregnant women with female fetuses no significant differences in levels of Tl comparing pregnant PE and Non PE, differing from those reported in the literature. Pregnant women with PE and female fetuses had significantly higher values of Tl that pregnant women no PE and male fetuses. Tl levels of PE and pregnant with male fetuses did not differ significantly from those with female fetuses and not PE. These results may indicate an androgenic influence in the pathophysiology of preeclampsia.

Palavras-chave : preeclampsia; chorionic gonadotropina; testosterone; hypertension.

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