Resumo

USECHE, Juan; NUNEZ, Elio  e  TORRES, Humberto. Agents involved in neonatal nosocomial infection and sensitivity pattern. Salus [online]. 2012, vol.16, n.3, pp.033-039. ISSN 1316-7138.

In order to determine the agents involved in nosocomial infections and their antimicrobial susceptibility in neonatology patients, a prospective study was carried out on 101 bacterial isolates, and cases of nosocomial sepsis were analyzed. We identified the susceptibility of strains by conventional microbiology with universal and selective culture media. Sensitivity was analyzed for estimation of rates for each 100 admissions. The incidence of nosocomial neonatal sepsis was 36.4%. Gram-negative bacteria (Klebsiella pn., Escherichia coli and non-fermenting) were predominant, 54.4%, followed by Gram-positive bacteria (Staphylococcus aureus and coagulase-negative Staphylococcus) 37.6%, and 7.9% fungi. Susceptibility to aminoglycosides was 28%. Sensitivity to ciprofloxacin for Klebsiella was 56.2%. Sensitivity of non-fermenters to cefepime and 3rd generation cephalosporins was 50%. Regarding meropenem, Escherichia coli was 54.4% sensitive, Klebsiella 65.5%, and non-fermenters 50%. Sensitivity of Escherichia coli, Klebsiella and nonfermenters to piperacillintazobactam was 45.4%, 40.6% and 50%, respectively. Sensitivity to colistin was 83.3% for non-fermenters, 71.8% for Klebsiella and 63.6% for Escherichia coli. Sensitivity of Staphylococcus aureus to oxacillin was 18.7%, and 100% to linezolid and vancomycin teicoplamina. Coagulase-negative Staphylococcus was 100% sensitive to linezolid, teicoplanin and vancomycin, and 46.6% to clindamycin. Results show stability of causal agents in the circulation, predominantly gram-negative bacteria and low susceptibility to antimicrobial therapy used.

Palavras-chave : neonatal nosocomial sepsis; susceptibility; Gramnegative bacteria.

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