Resumo

LEIVA HERNANDEZ, Aldoaneth Victoria; VARGAS, Adilen  e  LOZADA SANCHEZ, Carla Elizabeth. Evaluation of antifungal empirical therapy in patients with candidemia risk in the intensive care unit. Salus [online]. 2016, vol.20, n.3, pp.29-34. ISSN 1316-7138.

Candidemia is an important cause of deleterious changes in critically ill patients in intensive care units. Despite the importance of early diagnosis, in most cases a presumptive diagnosis is made. Given the risk it represents for the life of the patient and the difficulty in diagnosing it, in most cases candidemia treatment should be started empirically based on risk factors. Empirical anti-fungal therapy was assessed in patients with risk factors for candidemia admitted to the Intensive Care Unit of the “Dr. Enrique Tejera Hospital” between January and June 2014. In this prospective, observational, cross-sectional study, the sample consisted of 79 patients admitted to the intensive care unit. Neutropenic and oncology patients were excluded. Patients reported an average age of 32 years, 60.8% male. The most common risk factor for candidemia was use of central vein catheters. 35 received empirical antifungal therapy and of these 14 progressed satisfactorily. A total of 27 patients had Candida score >3 points. Most patients had more than one risk factor for candidemia; patients had an overall optimal response to empirical therapy. Candida Score was not a predictor of the success of empirical therapy.

Palavras-chave : Candidemia; risk factors; Candida Score; empirica antifungal therapy.

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