Resumen

FRONTADO ORTIZ, Freddy J. Análogos en el Régimen Basal/Bolo: Insulinización oportuna en diabetes tipo 2. Rev. Venez. Endocrinol. Metab. [online]. 2009, vol.7, n.1, pp.14-25. ISSN 1690-3110.

Diabetes is a difficult disease to treat. Currently, insulin is still the mainstay. Treatment strategies are aimed to reproduce the normal secretory profile of insulin to achieve the effective control in the fasting and postprandial plasma glucose levels. Mostly, with an appropriate combination of insulin analogues, an optimal control of blood sugar could be achieved, such as recommended by the different worldwide associations and organizations, dedicated to the study and control care of diabetes. This article is a review of the pathophysiology of Type 1 and Type 2 diabetes mellitus as the support for treatment in each one of its, but we still need to dispel myth and removing barriers of acceptance about these insulin regimens treatments in physicians and patients.

Palabras clave : Type 1 diabetes mellitus; basal/bolus insulin therapy; insulin analogues; type 2 diabetes mellitus; pancreatic insufficiency.