Resumen

BARRIOS, Yubire; MEERTENS, Lesbia; SALIM DE MORON, Alba  y  DIAZ, Nayka. Proteína C reactiva, su relación con el estado nutricional y perfil lipídico en mujeres posmenopáusicas. Rev. Venez. Endocrinol. Metab. [online]. 2011, vol.9, n.3, pp.106-111. ISSN 1690-3110.

Objective: In postmenopausal women increases the risk of cardiovascular disease (CVD) associated with an atherogenic lipid profile and elevated circulating levels of high-sensitivity C-reactive protein (hsCRP), considered important predictor proinflamatario marker for these diseases. The main purpose of this study was to evaluate the results of hsCRP and their relationship with nutritional state according to index of mass coporal (BMI) and lipid profile in postmenopausal women venezuelans Methods: 61 women were selected, healthy, residing in the municipality Naguanagua, aged between 45 and 60, apparently healthy. Nutritional status was classified according to BMI (WHO). We assessed hsCRP, lipid profile and estradiol. Results: Mean values of biochemical parameters were: hsCRP (3,16±2,0mg/L), total cholesterol (249±58mg/dL), HDL (42 ± 10mg/dL), LDL (176±55mg/dL), triglycerides (151±70mg/dL) and atherogenic index TC/HDL (6,2±1,9) y LDL/HDL (4,5±1,8). 60.7% category overweigh and obesity. 44.4% high risk according to hsCRP. The hazard ratio (OR), shows that the likelihood of women with normal nutritional status presented LDL-c values at risk was 0.485 (CI 95%: 0.230-0.999), while those who were overweight/obesity was 1.547 (CI 95%: 1.025-2.335). There was a significantly positive correlation between CRP and TC/HDL (r=0.418; p=0.001). Conclusions: Postmenopausal women presented a high prevalence of overweight/obesity, atherogenic lipid profile and CRP in risk for CVD.

Palabras clave : CRP; lipid profile; nutritional status; postmenopausal.