Resumen

GONZALEZ RIVAS, Juan Pablo. Síndrome metabólico: ¿Queda espacio para este concepto?. Rev. Venez. Endocrinol. Metab. [online]. 2012, vol.10, n.1, pp.20-27. ISSN 1690-3110.

The metabolic syndrome (MetS) is a cluster of metabolic risk factors in an individual which increase cardiovascular atherosclerotic disease (CAD) and type 2 diabetes (T2DM). This concept is not accepted completely. It is estimated that one third of people around the world have MetS. Two theories try to explain his physiopathology: obesity and insulin resistance; this because, not all patients with MetS have insulin resistance, and viceversa. The search for the analogy between these theories could be a mistake. From its description as X syndrome, many diagnosis criteria have been proposed for different associations, the NCEP/ATPIII criteria is the most accepted definition, which has suffered limited amendments since 2002; the most important change is the adjustment of waist circumference by race, recently proposing to Latin America, 94 cm for men and 90 cm for women. The predicted risk of MetS varies markedly according to the definition and criteria applied. The management of MetS involves controlling each of the alterations found; this notoriously weakens its diagnostic need. We conclude that the MetS is an instrument to detect patients at risk of CAD and T2DM, mostly in epidemiological studies, leaving a space primarily oriented to the study of pathophysiology and epidemiological evaluation of this concept. We make a revision of these topics.

Palabras clave : Metabolic Syndrome; Obesity; Insulin Resistance; Cardiometabolic Risk; Controversy.

        · resumen en Español     · texto en Español     · Español ( pdf )