Resumen

GONZALEZ RIVAS, Juan Pablo. Diabetes ¿Un concepto enfocado en reducción de riesgo cardiovascular?. Rev. Venez. Endocrinol. Metab. [online]. 2013, vol.11, n.1, pp.3-8. ISSN 1690-3110.

Cardiovascular disease (CVD) is leading death cause en patients with diabetes mellitus (DM). Observational epidemiologic data indicated that highest A1c levels are associated with highest risk of CVD; however, recent research suggests that in patients with established CVD or risk factors, achieving goals for glycemic control, insulin glargine start early, or a sustained weight loss for 5 years with lifestyle changes, do not provide a benefit risk reduction in all-cause mortality including cardiovascular mortality. One study with prolonged follow-up demonstrates a little benefit on macrovascular outcomes and mortality in patients with short duration of DM and low cardiovascular risk. Most studies agree that demonstrate benefits in treating intensively microvascular blood glucose, an effect that is possibly due to the diagnostic criteria for DM are based on findings of microvascular disease, suggesting the need to develop new diagnostic tools in DM his intervention strongly to reduce the occurrence of CVD. This definition probably should precede the onset of hyperglycemia, the answer may be in determining insulin resistance, however, currently there is no reliable tools for the detection of this disorder.

Palabras clave : Diabetes mellitus; Mortality; Cardiovascular disease; Insulin resistance.

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